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KMID : 1141320170320010118
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Kosin Medical Journal
2017 Volume.32 No. 1 p.118 ~ p.126
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A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjogren's Syndrome
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Yun Yeong-Seop
Choi Ji-Wook
Doo Young-Jae
Kim Tae-Hyung
Oh Hye-Lim
Oh Ji-Min
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Abstract
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Sjogren’s syndrome is a systemic autoimmune disease characterized by sicca symptoms and extraglandular manifestations. Anemia, leukopenia, thrombocytopenia and lymphoproliferative disorders are well-known extraglandular, hematological complications of Sjogren’s syndrome. These hematologic alterations are usually mild and respond well with steroid therapy. We report a case of a 52-year-old female patient who was initially presented with thrombocytopenia. The patient was then diagnosed with primary Sjogren’s syndrome and initially treated with steroid. The patient’s platelet count was decreased when steroid was tapered. The dose of steroid could be effectively reduced after combined medication with hydroxychloroquine.
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KEYWORD
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Hydroxychloroquine, Primary Sjogren’s syndrome, Steroid, Thrombocytopenia
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